An ophthalmic lens, such as an intraocular lens (lOL), a phakic lOL or a corneal implant, and a system and method relating to same, having coupled thereto and/or integrated thereon at least one rotationally asymmetric diffractive structure. The lens of the present invention may include a single or limited number of rotationally asymmetric diffractive echelettes that provides an extended depth of focus.