Pharmaceutical composition comprising an antibody against oxidized LDL receptor

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专利权人:

眞崎 知生;沢村;達也;沢村 達也

发明人:

沢村 達也,眞崎 知生,角谷 真,岩村 浩幸

申请号：

JP2010037328

公开号：

JP5232818B2

申请日:

2010.02.23

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To provide an anti-oxidized LDL receptor (LOX-1) antibody having potency to inhibit binding of a ligand by binding to the LOX-1 and able to be used as a pharmaceutical composition. <；P>；SOLUTION: The anti-LOX-1 antibody which is a human monoclonal antibody, and a fragment peptide having potency to bind to the LOX-1 and cells for producing the antibody are provided. The antibody can be used as a prophylactic-therapeutic composition for various inflammatory diseases, arteriosclerosis. post-operative blood vessel restenosis of PTCR and PTCA, and the like. <；P>；COPYRIGHT: (C)2010,JPO&INPIT

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