CHARLES J. COX,COLIN F. SPRAGGS,LAURA R. BUDDE,LINDA PERRY BRILEY,NAN BING
申请号:
BR112012003653
公开号:
BR112012003653A2
申请日:
2010.08.20
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein said patient does not have one or more allelic polymorphisms selected from the group of: HLA-DQA1*0201, HLA-DQB1*0202, and HLA-DRB1*0701. Patients may also be free of genotypes in TNXB; rs12153855 and/or rs17207923.