Disclosed herein are compositions for lowering intraocular pressure (IOP) of an eye comprising a combination of the IOP-lowering agents bimatoprost, brimonidine, and timolol. Further disclosed are methods for reducing IOP in the eye of a subject.COMPOSICION FARMACEUTICA QUE COMPRENDE BIMATOPROST, BRIMONIDINA TARTRATO Y TIMOLOL MALEATO; SU USO PARA REDUCIR LA PRESIÓN INTRAOCULAR.