Jerry Evarts,Joshua Kaplan,Musong Kim,Leena Patel,Stephane Perreault,Gary Phillips,Jennifer A. Treiberg,Joshua Van Veldhuizen
申请号：
US14304539
公开号：
US09221795B2
申请日:
2014.06.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (I),or pharmaceutically acceptable salts or isomers thereof, in which n, m, R1, R2, R4, and R3 are as defined herein. These compounds are useful for treatment of conditions mediated by one or more PI3K isoforms, such as PI3Kδ. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts or isomers thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3Kδ.
