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Method and apparatus for the manufacture of fibrous dosage forms
专利权人:
Aron H. Blaesi
发明人:
Aron H. Blaesi,Nannaji Saka
申请号:
US15964058
公开号:
US20180271797A1
申请日:
2018.04.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Recently, we have introduced fibrous dosage forms that enable predictable microstructures with a greater range of pharmaceutically relevant properties. Presented herein, accordingly, are a method and an apparatus for the manufacture of such fibrous dosage forms. The method includes extruding a plasticized matrix through an exit port of an extrusion channel to form at least one plasticized fiber, and structuring said at least one plasticized fiber to a three dimensional structural network of fibers. The apparatus includes an internally hollow housing defining an extrusion channel, a conveying element for extruding a plasticized matrix in the extrusion channel through an exit port to form at least one plasticized fiber, and a unit for structuring said at least one plasticized fiber to a three dimensional structural network of fibers.
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