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COMPOUNDS AND METHODS OF TREATING USHER SYNDROME III
专利权人:
发明人:
Kumar N. Alagramam
申请号:
US15525270
公开号:
US20180282382A1
申请日:
2015.11.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An isolated polynucleotide includes a nucleic acid sequence that includes a cDNA coding sequence of a clarin-1 gene and a 3′UTR nucleic acid that is derived from the 3′UTR of the clarin-1 gene. The 3′UTR nucleic acid can enhance expression of clarin-1 in a cell transfected with the polynucleotide compared to a cell transfected with a similar polynucleotide devoid of the 3′UTR nucleic acid.
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