Miquel Àngel Gassull Duro,Adolfo Rio Fernandez,Ester Fernandez Gimeno,Miguel Chillón Rodriguez
申请号:
US13266763
公开号:
US20120045389A1
申请日:
2010.04.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a biosafe and useful vector to transfer genetic material to CD14+ mononuclear cells (monocytes and monocyte-derived macrophages) in an efficient and specific manner. The embodiment of the invention makes use of the chimeric human adenovirus vectors 5 carrying the short fiber of enterotropic Ad40 to transfer genetic material to the target CD14+ mononuclear cells.