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METHODS AND REAGENTS FOR EFFICIENT AND TARGETED GENE TRANSFER TO MONOCYTES AND MACROPHAGES
专利权人:
Miquel Àngel Gassull Duro
发明人:
Miquel Àngel Gassull Duro,Adolfo Rio Fernandez,Ester Fernandez Gimeno,Miguel Chillón Rodriguez
申请号:
US13266763
公开号:
US20120045389A1
申请日:
2010.04.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a biosafe and useful vector to transfer genetic material to CD14+ mononuclear cells (monocytes and monocyte-derived macrophages) in an efficient and specific manner. The embodiment of the invention makes use of the chimeric human adenovirus vectors 5 carrying the short fiber of enterotropic Ad40 to transfer genetic material to the target CD14+ mononuclear cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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