Natural ligand of G protein coupled receptor RCC356 and uses thereof

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专利权人:

Chemcom S.A.

发明人:

Veithen, Alex,Philippeau, Magali,Sallmann, Frederic

申请号：

AU2006222265

公开号：

AU2006222265B2

申请日:

2006.03.02

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The invention relates to the identification of isovaleric acid as a natural ligandof the RCC356 G-protein coupled receptor (GPCR). The invention encompassesthe use of the interaction of RCC356 polypeptides and isovaleric acid as the basisof screening assays for agents that modulate the activity of the RCC356 receptor.The invention also encompasses diagnostic and other assays performed basedupon the RCC356/isovaleric acid interaction, as well as kits for performingdiagnostic and screening assays.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/