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FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS
专利权人:
JANSSEN PHARMACEUTICA; N.V.
发明人:
MACDONALD GREGOR JAMES,MACDONALD Gregor James,LANGLOIS XAVIER JEAN MICHEL,LANGLOIS Xavier Jean Michel,BARTOLOME-NEBREDA JOSE MANUEL,BARTOLOME-NEBREDA Jose Manuel,VAN GOOL MICHIEL LUC MARIA,VAN GOOL Mi
申请号:
SI200830804
公开号:
SI2121630T1
申请日:
2008.02.11
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
The present invention relates to 4-aryl-6-piperazin-1-yl-3-substituted-pyridazines of formula (I) that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.
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