The present invention relates to a skin administration system capable of ensuring the stability of peptides or proteins and enhancing the delivery rate of peptides or proteins through the skin and, more particularly, to a microneedle comprising peptides or proteins.本發明涉及一種確保了肽或蛋白質的穩定性,並能夠提高上述肽或蛋白質的皮膚透過率的透皮給藥系統,尤其是,涉及一種包含肽或蛋白質的微針。