Mattheus Cornelis De Wilde;Martine Groenendijk;Patrick Joseph Gerardus Hendrikus Kamphuis;Robert Johan Joseph Hageman
发明人:
Robert Johan Joseph Hageman,Mattheus Cornelis De Wilde,Martine Groenendijk,Patrick Joseph Gerardus Hendrikus Kamphuis
申请号：
US13977168
公开号：
US20130331352A1
申请日:
2011.12.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Composition comprising at least two components, more preferably at least three components, more preferably at least four components, selected from the group of (i) a nucleoside equivalent, (ii) an ω-3 polyunsaturated fatty acid selected from the group of DHA, DPA and EPA, (iii) a vitamin B, (iv) a phospholipid, (v) an antioxidant and (vi) a choline, with the proviso that at least component (i) or (iii) is present, for use in the prevention or treatment of frailty in a mammal, wherein frailty is determined by compliance with at least 2 criterions, preferably 3 criterions, selected from the group of muscle weakness, excessive feelings of exhaustion or fatigue, abnormally low physical activity, slow or unsteady gait, weight loss, and neurological dysfunction.
