ANTI-C-MET ANTIBODY FORMULATIONS

• 收藏
• 分享

专利权人:

GENENTECH; INC.

发明人:

KABAKOFF, Bruce,LIU, Jun,PIROS, Nicole,ZHU, Qing,DEMEULE, Barthelemy

申请号：

USUS2012/044829

公开号：

WO2013/003680A8

申请日:

2012.06.29

申请国别(地区):

WO

年份:

2013

代理人:

摘要：

Provided herein are pharmaceutical formulations comprising a one-armed, anti-c-met antibody, wherein the anti-c-met antibody comprises a HVR-L1 comprising sequence KSSQSLLYTSSQKNYLA (SEQ ID N0:1), a HVR-L2 comprising sequence WASTRES (SEQ ID NO: 2), a HVR-L3 comprising sequence QQYYAYPWT (SEQ ID N0:3), a HVR-HI comprising sequence GYTFTSYWLH (SEQ ID N0:4), a HVR-H2 comprising sequence GMIDPSNSDTRFNPNFKD (SEQ ID NO: 5), and a HVR-H3 comprising sequence ATYRSYVTPLDY (SEQ ID NO: 6) and uses of the same.La présente invention concerne des formulations pharmaceutiques comprenant lanticorps onartuzumab anti-c-met à un bras, ainsi que des utilisations desdites formulations.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/