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FARMACINĖ KOMPOZICIJA, APIMANTI LACIDIPINĄ IR JOS GAVIMO BŪDAS
专利权人:
Rivopharm SA
发明人:
Poli, Piero,Carcano, Michela,Vecchi, Gabriele
申请号:
LT13183603
公开号:
LT2705839T
申请日:
2013.09.09
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
The invention relates to a solid pharmaceutical composition comprising lacidipine and polyvinylpyrrolidone, wherein the weight ratio of lacidipine to polyvinylpyrrolidone is about 10/90. The invention also relates to a process for preparing said composition comprises the step of: a) providing a solution of polyvinylpyrrolidone and lacidipine in a polar solvent, b) spraying the solution of step a) onto a solid diluent, so as to obtain granules, c) optionally, adding to the granules obtained in step b) at least one additional excipient preferably selected from a glidant, a lubricant, a diluent and combinations thereof, and d) shaping the resulting granules into a solid form, preferably into a tablet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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