A miniature endoscope with an imaging arrangement associated with its distal tip portion includes an image sensor chip with a two-dimensional array of light-sensitive pixels and a lens arrangement deployed for focusing light from a field of view onto the image sensor chip so as to generate an image of a scene viewed from the distal tip portion. The lens arrangement is preferably directly affixed to the image sensor chip by a quantity of transparent adhesive. Use of bidirectional communication along data lines to the image sensor chip allows use of only four wires connecting to the chip. These and other features allow miniaturization of the endoscope to a diameter of about 2 millimeters while still generating color images of high dynamic range.
