Devices, and methods for synchronizing cerebro-hemodynamic signals are disclosed. In one aspect, the devices and methods may include synchronizing first and second signals indicative of hemodynamic characteristics within a subjects brain. Differences may be determined between the synchronized signals and used to provide information for diagnosing changes in arterial occlusion. Differences between the synchronized signals may include differences, such as timing delays, between signature features of the synchronized signals. The first and second signals may be indicative of hemodynamic characteristics in first and second hemispheres of a subjects brain. The first and second signals may be bioimpedance signals.