A nicotine-containing particulate material for release of nicotine, thematerial comprising a combination of nicotine or a pharmaceutically acceptablesalt, complex or solvate thereof and a microcrystalline cellulose, Theparticulate material is stable upon storage and releases nicotine relativelyfast. The particulate material can be used in the manufacture of nicotine-containing pharmaceutical composition, wherein the release of nicotine can bedesigned to be relatively fast so as to obtain a fast onset of action.