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SALTS AND SOLID FORM OF A BTK INHIBITOR
专利权人:
PRINCIPIA BIOPHARMA INC.
发明人:
Mohammad Reza MASJEDIZADEH,Steven GOURLAY
申请号:
US16596611
公开号:
US20200038405A1
申请日:
2019.10.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are processes for preparing 2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile free base (compound (I)), salts of compound (I) and solid state form of said salts. Also disclosed herein are pharmaceutical compositions comprising such salts and solid state form thereof and methods of treating cancer, autoimmune, and inflammatory diseases using compound (I) or a pharmaceutically acceptable salt thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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