NATURALLY OCCURRING miRNA FOR CONTROLLING GENE EXPRESSION, AND USE OF SAME

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专利权人:

BONAC CORPORATION

发明人:

Eriko AOKI,Yasuhiko YOSHIDA,Shiori KATO,Tadaaki OHGI

申请号：

US15539226

公开号：

US20180326091A1

申请日:

2015.12.25

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides a natural type miRNA,which is a single-stranded nucleic acid containing X region and Y region,wherein the 3′-terminus of said X region and the 5′-terminus of said Y region are linked via a linker region of a non-nucleotide structure,the X region contains (a) a guide strand sequence or (b) a passenger strand sequence of a mature miRNA,when the X region contains (a), the Y region contains a passenger strand sequence of the mature miRNA,when the X region contains (b), the Y region contains a guide strand sequence of the mature miRNA, andthe guide strand sequence and the passenger strand sequence form a double-stranded structure.

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