The present invention relates to the biomedical field, and in particular, to a glucose parent nucleus, comprising glucose and/or glucose hydrate, a diluent and adhesives. The content of the glucose and/or the glucose hydrate in the glucose parent nucleus is less than or equal to 85% according to the weight percentage. The present invention also relates to a glucose pellet, comprising a glucose parent nucleus and a laminated layer coating the glucose parent nucleus. Further, the present invention also relates to a pharmaceutical composition containing the glucose pellet. The glucose pellet or a pharmaceutical composition in the present invention can treat and/or assist in treating glycogen storage diseases and/or diabetes.
