Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-alpla]pyrrolo[2,3-e]-pyrazin-8-YL)-N-(2,2,2-Trifluoroethyl)pyrrol and solid state forms thereof
Jayanthy Jayanth,Patrick J. Marroum,Peter T. Mayer,Mohamed-Eslam F. Mohamed,Ahmed A. Othman
申请号:
US15857892
公开号:
US09963459B1
申请日:
2017.12.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.