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Terpene derivative exhibiting apoptosis-inducing action and method for producing the same
专利权人:
二村;芳弘
发明人:
二村 芳弘
申请号:
JP2007253450
公开号:
JP5231777B2
申请日:
2007.09.28
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
<;P>;PROBLEM TO BE SOLVED: To provide a terpene derivative providing weak side effects and exhibiting excellent apoptosis-inducing activity, and to provide a method for producing the terpene derivative. <;P>;SOLUTION: The terpene derivative providing the weak side effects and exhibiting the excellent apoptosis-inducing activity has -1 mV to -600 mV oxidation-reduction potential. The derivative has a tripeptide consisting of cysteine, glycine and cysteine bonded to a hydroxy group of a terpene by an ester bond. The cysteine, the glycine and the cysteine are peptide-bonded. The method for producing the derivative includes steps of adding soybean powder and Bacillus natto to a powder of a persimmon leaf or a powder of a pine leaf, fermenting the resultant mixture, filtering the fermented liquid, and reducing the resultant filtrate using an alkali, the main steps therein being the fermentation step and the alkali reduction step. <;P>;COPYRIGHT: (C)2009,JPO&INPIT
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