Medical appliance securing device and method of using the same to secure a medical appliance to a patient. In one embodiment, the device may be used to secure a hemodialysis catheter to a patient and may include a first base portion, a first adhesive for securing the first base portion to an object, such as a patient, the first adhesive being positioned under and coupled to the first base portion, a second base portion, the second base portion being positionable over the first base portion and fastenable to the first base portion and a strap, the strap having a first end coupled to the first base portion and a second end fastenable to the second base portion.