The United States of America; as represented by the Secretary; Dept. of Health and Human Services
发明人:
Juan Jose Marugan,Wei Zheng,Jingbo Xiao,John McKew
申请号：
US15608753
公开号：
US10370348B2
申请日:
2017.05.30
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The subject invention relates to improved tocopheryl quinine derivatives and tocopherol derivatives having improved pharmacokinetics in vivo that can, in some embodiments, be useful in the treatment of Lysosomal Storage Disorder, restoration of normal mitochondrial ATP production, modulation of intracellular calcium ion concentration and other treatments or therapies. The tocopheryl quinone derivatives and tocopherol derivatives have side chains that have terminally halogenated carbon atoms.
