The present invention relates to: a tubular medical device cleaning ball; and a manufacturing method therefor and, more specifically, to: a tubular medical device cleaning ball capable of cleaning a tubular medical device by being injected together with a cleaning solution without using a separate brush and the like in order to clean the tubular medical device inserted into the human body during minimally invasive surgery; and a manufacturing method therefor. To this end, the cleaning ball is manufactured as a sphere having surface roughness and a cavity therein.