Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers

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专利权人:

Fred Hutchinson Cancer Research Center

发明人:

Stephan, Matthias,Moffett, Howell F.

申请号：

AU2017250295

公开号：

AU2017250295A1

申请日:

2017.04.14

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Compositions and methods that rapidly and selectively modify hematopoietic stem cells (or cells derived therefrom) to achieve therapeutic objectives by providing for transient expression of nucleic acids are described. The transient expression leads to permanent therapeutic changes in the modified cells, referred to herein as "hit and run" effects.

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中国工程科技知识中心

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http://www.ckcest.cn/home/