LIZIO, ROSARIO,GRIMM, SILKO,PETEREIT, HANS-ULRICH,EPPLE, MATTHIAS,DORDELMANN, GREGOR
申请号:
CA2950339
公开号:
CA2950339A1
申请日:
2015.05.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention refers to a nanoparticle with a diameter which is the maximum in the nanoparticle size distribution,in the range of 10 300 nm, comprising a) a calcium phosphate nanoparticle core a), b) an active ingredient coating b) on the calcium phosphate nanoparticle core a), c) a lactic acid polymer coating c) on the active ingredient coating b), d) a cationic polymer coating d) on the lactic acid polymer coating c) selected from the group of polyethylene-imines, chitosan and human lactoferrin- derived peptides with a length of 14 to 30 amino acids.