A modified release pharmaceutical composition for treating premature ejaculation. The above composition comprises full quantitative timely release (FQTR)of therapeutically effective amounts of active compounds comprising tramadol, rabeprazole, cetirizine, sildenafil or their pharmaceutically acceptable salts thereof. Full quantitative timely release of the pharmaceutical composition comprises total and immediate release of the prescribed doses at the specified time and at once, for delaying the onset of ejaculation by at least 20 minutes irrespective of non-medicated time delay.
