Karen Wooley,Jiong Zou,Mahmoud El Sabahy,Shiyi Zhang,Fuwu Zhang
申请号:
US14043456
公开号:
US09545447B2
申请日:
2013.10.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure generally relates to polymer-drug systems, and more particularly to nanoscopic particles comprising amphiphilic block copolymers conjugated, physically encapsulated, or otherwise combined with chemotherapeutic agents along a selective region or regions of the backbone of the copolymer, so as to package the chemotherapeutic agent in selective domains within each nanoscopic particle, as well as to methods for making such particles, and applications and methods for using such particles, including in the formation of polymer micelles.