A nutritional supplement composition having therapeutically effective amounts of milk minerals including calcium, a protein source including K-casein fragment 106-169, and enzyme-inhibiting peptides is provided for the treatment of body weight conditions. The nutritional supplement composition is administered in amounts effective for limiting weight gain and/or enhancing weight loss, as well as promoting overall good health, in the treatment of body weight conditions, including overweight and obesity. One claim is directed to compositions including angiotensin-converting enzyme inhibiting peptide for controlling fat metabolism.