An object of the present invention is to provide a pharmaceutical composition which contains compound I having a good dissolvability in a neutral range, pharmacologically acceptable salts thereof or their solvates, as an active ingredient. The present invention relates to a pharmaceutical composition which contains: (A)N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl) ethanediamide, pharmacologically acceptable salts thereof or their solvates, and (B) acids or salts thereof.本發明之課題係提供一種醫藥組成物,其含有於中性區域中溶出良好的化合物I、其藥理上可容許之鹽或該等溶劑合物作為有效成分。本發明係關於一種醫藥組成物,其含有:(A)N1-(5-氯吡啶-2-基)-N2-((1S,2R,4S)-4-[(二甲基胺基)羰基]-2-{[(5-甲基-4,5,6,7-四氫噻唑并[5,4-c]吡啶-2-基)羰基]胺基}環己基)乙二醯胺、其藥理上可容許之鹽或該等溶劑合物,及(B)酸或其鹽。