The present invention provides a compound of formula (I): wherein: €¢ R 1 is a group selected from -CH 2 OH, -NHC(O)H and €¢ R 2 is a hydrogen atom； or €¢ R 1 together with R 2 form the group -NH-C(O)-CH=CH- wherein the nitrogen atom is bound to the carbon atom in the phenyl ring holding R 1 and the carbon atom is bound to the carbon atom in the phenyl ring holding R 2 €¢ R 3 is selected from hydrogen and halogen atoms or groups selected from -SO-R 5 , -SO 2 -R 5 , -NH-CO-NH 2 , -CO-NH 2 , hydantoino, C 1-4 alkyl, C 1-4 alkoxy and -SO 2 NR 5 R 6 €¢ R 4 is selected from hydrogen atoms, halogen atoms and C 1-4 alkyl groups €¢ R 5 is a C 1-4 alkyl group or C 3-8 cycloalkyl €¢ R 6 is independently selected from hydrogen atoms and C 1-4 alkyl groups €¢ n, p and q are independently 0, 1, 2, 3 or 4 €¢ m and s are independently 0, 1, 2 or 3 €¢ r is 0, 1 or 2 with the provisos that: €¢ at least one of m and r is not 0 €¢ the sum n+m+p+q+r+s is 7, 8, 9, 10, 11, 12 or 13 €¢ the sum q+r+s is 2, 3, 4, 5 or 6 or a pharmaceutically-acceptable salt, solvate or stereoisomer thereof.本發明提供式(I)化合物：及其醫藥學上可接受之鹽或溶劑合物或立體異構體，其具有β2腎上腺素受體激動劑活性，且可用於治療與β2腎上腺素受體激動劑活性相關之疾病或病情，例如肺部疾病，諸如哮喘或慢性阻塞性肺部疾病、早產、青光眼、神經病症、心臟病症或炎症。本發明亦提供一包含本發明之化合物及醫藥學上可接受之載劑之醫藥組合物。本發明進一步提供包含本發明之化合物及一或多種其他治療劑之組合，及包含此等組合之醫藥組合物。
