ABDIN MALIK ZAINUL,ABDIN MALIK ZAINUL,AHMAD FARHAN JALEES,AHMAD FARHAN JALEES,HEJAZI MOHAMMAD SAEID,HEJAZI MOHAMMAD SAEID,ALVARI AMENE,ALVARI AMENE,RAFSANJANI MEHRNAZ SADAT OHADI,RAFSANJANI MEHRNAZ SA
申请号：
IN306/DEL/2012
公开号：
IN2012DE00306A
申请日:
2012.02.03
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The present invention relates to a novel nano-vesicular composition comprising of Phyllanthus amarus and Cichorium intybus extracts, phytoconstituents Phyllanthin and esculin having improved oral bioavailability, efficacy and Hepatoprotective effect. More particularly, the present invention relates to a novel lipidic nano-vesicular Hepatoprotective composition comprising a biocompatible natural lipid, cholesterol and/or biocompatible, non-irritant surfactants, Phyllanthus amarus and Cichorium intybus species extract and phytoconstituents Phyllanthin and esculin. In addition, the lipid nano vesicular composition is encapsulated with extract/bioactives resulting into improved oral bioavailability up to ten fold with improves bio-efficacy and controlled delivery.
