BLATTER, FRITZ,INGALLINERA, TIM,BARF, TJEERD,ARET, EDWIN,KREJSA, CECILE,EVARTS, JERRY
申请号：
CA2991096
公开号：
CA2991096A1
申请日:
2016.07.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
In some embodiments, the invention relates to crystalline solid forms, including polymorphs, hydrates, and salt forms, of(S)-4-(8-amino-3-(1 -(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-l-yl)-N-(pyridin-2-yl)benzamide. In some embodiments, the invention also relates to pharmaceutical compositions containing the crystalline solid forms, and methods for treating conditions or disorders by administering to a subject a pharmaceutical composition that includes the forms, including pharmaceutical compositions and methods for overcoming the effects of acid reducing agents. Formula (I)
