NOVEL GLYCINE AMIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH SODIUM CHANNEL ACTIVATION CONTAINING SAME
EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION
发明人:
PARK, HEA YOUNGKR,박혜영,YUNE, TAE YOUNGKR,윤태영,OH, JUNG AEKR,오정애
申请号：
KR1020160010605
公开号：
KR1020170090547A
申请日:
2016.01.28
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a novel glycine amide compound or a pharmaceutically acceptable salt thereof, a production method thereof, and a pharmaceutical composition for preventing or treating diseases associated with sodium channel activation containing the same. According to the present invention, the novel glycine amide compound excellently inhibits Nav 1.7 channels, and is also excellent in suppression of neuropathic pain. Accordingly, the novel glycine amide compound can be useful as pharmaceutical compositions for preventing and treating neuropathic pain containing the same.COPYRIGHT KIPO 2017본 발명은 신규한 글라이신 아미드 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 소듐 채널 활성 관련 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 화합물은 Nav 1.7채널 억제활성이 우수하고 신경병성 통증 억제 활성이 우수하므로, 이를 함유하는 신경병성 통증의 예방 및 치료를 위한 약학적 조성물로 유용하게 사용될 수 있다.
