ENHANCEMENT OF EXPRESSION OF A SINGLE-STRANDED, HETEROLOGOUS NUCLEOTIDE SEQUENCE FROM RECOMBINANT VIRAL VECTORS BY DESIGNING THE SEQUENCE SUCH THAT IT FORMS INSTRASTRAND BASE PAIRS

• 收藏
• 分享

专利权人:

TARGETED GENETICS CORPORATION

发明人:

CARTER, BARRIE

申请号：

CA2379166

公开号：

CA2379166C

申请日:

2000.08.08

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

Recombinant viral vectors, especially parvovirus such as adeno-associatedvirus (AAV) vectors, capable of enhanced expression of heterologous sequences,and methods for their construction and use, are provided. The vectors have astructure, or are capable of rapidly adopting a structure, which involvesintrastrand base pairing of at least one region in a heterologous sequence.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/