Thomas C. Riley;Robert C. Cuca;Elio Mariani;R. Saul Levinson
发明人:
Thomas C. Riley,R. Saul Levinson,Robert C. Cuca,Elio Mariani
申请号：
US13555472
公开号：
US20130102548A1
申请日:
2012.07.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A pharmaceutical formulation to treat vaginal conditions in a human patient comprises:at least one active agent；a modified release dosage form which provides extended release of the anti-infective agent upon vaginal administration to the patient； andwherein the formulation, when containing a total dose of the anti-infective agent of about 25 μg to about 500 mg based on the active agent will produce a plasma concentration versus time curve (ng/mL versus hours) having an area under the curve (AUC) of less than about 600 ng/mL·hr.
