BARR CHARLA,DOBISH MARK C,SMITH BRIAN J,STEFANICK STEPHEN M
申请号:
IN201617014849
公开号:
IN201617014849A
申请日:
2016.04.28
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention is directed to an improved process for the preparation of methylphenidate stereoisomer mixture of stereoisomers and pharmaceutically acceptable salts thereof more particularly the sulfate and hydrochloride salts of methylphenidate di threo methylphenidate and dex methylphenidate. Methods of removing or reducing the amount of impurities from the above described process are also disclosed.