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Allorestricted peptide-specific T cells
专利权人:
Angela Krackhardt;Dirk Busch;Ingrid Schuster
发明人:
Angela Krackhardt,Ingrid Schuster,Dirk Busch
申请号:
US12304918
公开号:
US08217009B2
申请日:
2007.06.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a T cell receptor (TCR) recognizing antigenic peptides derived from tumor-associated antigen FMNL1/KW13 and being capable of inducing peptide specific killing of a target cell. The present invention is further directed to one antigenic peptides derived from tumor-associated antigen FMNL1/KW13, to an antigen specific T cell, comprising said TCR, to a nucleic acid coding for said TCR and to the use of the antigen specific T cells for the manufacture of a medicament for the treatment of malignancies characterized by overexpression of FMNL1/KW13.
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