Hindi, Khadijah,Medvetz, Douglas A.,Youngs, Wiley J.
申请号：
AU2008260203
公开号：
AU2008260203B2
申请日:
2008.05.29
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The invention is directed to providing a compound for treating cancer, the compoundcomprising a metal complex having predetermined characteristics, and whichmay be incorporated into a polymeric nanoparticle or other delivery system fordelivering the metal complex for action on tumor cells. The metal complex fortreating cancer wherein the metal complex is a silver(I) salt, a silver(I) macrocyclicmetal complex, a silver(I) N-heterocyclic carbene or mixtures thereof. Theinvention is also directed to a silver(I) macrocyclic metal complex and a silver(I)N-heterocyclic carbine, and methods of treating cancerous cells in a mammalincluding the steps of administering an effective amount of a silver(I) metalsalt, such as by incorporating the material into a biodegradable polymeric nanoparticle.
