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PROCÉDÉ DE FABRICATION DE COMPRIMÉS À GRANULATION PAR VOIE HUMIDE UTILISANT UNE DISPERSION AQUEUSE DE CELLULOSE HYDROXYPROPYLE SUBSTITUÉE FAIBLE
专利权人:
SHIN-ETSU CHEMICAL CO.; LTD
发明人:
申请号:
EP16152911.0
公开号:
EP3031451A1
申请日:
2010.01.25
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Provided is a method for preparing a tablet having high tablet hardness and an excellent disintegration property even if low-substituted hydroxypropyl cellulose is added in a relatively small amount. More specifically, provided is a method for preparing a tablet comprising steps of granulating while spraying an aqueous dispersion of low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxyl group substitution ranging from 5 to 16% by weight to a tablet-forming composition to obtain compression-moldable granules and tableting the granules whose surfaces have been modified with the low-substituted hydroxypropyl cellulose to obtain the tablet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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