A hand powder composition, particularly useful for musicians of necked stringed instruments, comprising a fine moisture absorbing powder in an amount from about 90%-99% by weight of the total composition and a fine polytetrafluoroethylene powder in an amount from about 1%-7% by weight of the total composition. The polytetrafluoroethylene powder may have average particle sizes of about 18-22 μm. The moisture absorbing powder may be talcum powder or corn starch, or a combination thereof. A fine alkaline powder may be included to neutralize acidity of perspiration. A fine powdered colorant may be included for approximately matching the color of the composition to a desired color.