Chunlin Tao,Qinwei Wang,Sharif Asad,Paul Weingarten,Sherry Ci
申请号：
US15992989
公开号：
US20180346451A1
申请日:
2018.05.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to the use of substituted pyrimidine derivatives to modulate tropomyosin-related kinase (Trk) family protein kinase, and the use of the substituted pyrimidine derivatives for the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
