ECKELMAN, BRENDAN,TIMMER, JOHN,RAZAI, AMIR,DEVERAUX, QUINN,JONES, KYLE,LAPPE, MARK
申请号：
PE2015001628
公开号：
PE20151408A1
申请日:
2013.08.06
申请国别(地区):
PE
年份:
2015
代理人:
摘要：
The invention is generally related to monoclonal antibodies with carcinogenic effect of CD47, and more specifically, antibodies with carcinogenic effect of CD47, which will not cause a large number of cell aggregation, red cell failure, anemia and / or platelet failure, methods of producing these antibodies and methods of using these antibodies. Monoclonal antibody as therapeutic agentEsta invencion se relaciona de manera general con anticuerpos monoclonales que reconocen CD47, mas especificamente con anticuerpos CD47 que no provocan un nivel significativo de aglutinacion de celulas, agotamiento de globulos rojos, anemia, y/o agotamiento de plaquetas, con metodos para generar estos anticuerpos, y con metodos para utilizar estos anticuerpos monoclonales como agentes terapeuticos
