The present invention relates to an expandable plug body for use in a vagina which is expandable at a predetermined value in an aqueous solution and has an expansion value of 1 to 30 at saturated water absorption. Effective components may be immersed in the interior of the expandable plug body, or dissolved and dispersed in the material wrapping the expandable plug body. The expandable plug body is primarily used in the vagina. The present invention provides an expandable plug body having some unique physical properties such as expanding at a predetermined expansion value, expanding at a specific pH value, and periodically expanding, so that it has a good performance when used as a medicine, a cosmetic, and a disinfection product. After the application of the original liquid of the expandable plug body onto the vagina for 3˜5 min, antibacterial rates of which on E. coli, Staphylococcus aureus and Candida albicans are all in the range of 89˜95%.
