Provided herein are kits and methods for improving bone regeneration, in particular guided bone regeneration (GBR) in oral surgery prior to implant placement, particularly in maxillary sinus augmentation (GBR-MSA). It has been shown that GBR-MSA with a combination of i) unmodified autologous adipose-derived regenerative cells (UA-ADRCs), ii) a fraction of plasma rich in growth factors (PRGF-2), and iii) an osteoinductive scaffold (OIS) is effective, leading to a significant increase in the relative amount of newly formed bone and of dense fibrous tissue as well as less unwanted new adipose tissue formation without adverse effects.
