Roey Jacob AMIR,Marina BUZHOR,Assaf Josef HARNOY,Ido ROSENBAUM,Liat FRID
申请号：
US15509946
公开号：
US20170245492A1
申请日:
2015.02.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to an amphiphilic hybrid delivery system in micellar form for delivery of agrochemicals, based on a hydrophilic polyethylene glycol (PEG) polymer conjugated to a hydrophobic dendron, the dendron comprising at least one pH-dependent or enzymatically cleavable hydrophobic end group that is covalently attached to the dendron, wherein the micelle disassembles upon enzymatic or pH-dependent cleavage of the hydrophobic end group. The hydrophobic end group that is conjugated to the dendron may comprise an agrochemical, and/or the micelle may (non-covalently) encapsulate an agrochemical. The present invention further provides methods of use thereof and to a kit comprising same.
