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MODULATEURS DU RECEPTEUR DE LA SPHINGOSINE -1-PHOSPHATE POUR LE TRAITEMENT DE TROUBLES CARDIO-PULMONAIRES
- 专利权人:
- THE SCRIPPS RESEARCH INSTITUTE
- 发明人:
- ROBERTS, EDWARD,ROSEN, HUGH,URBANO, MARIANGELA,GUERRERO, MIGUEL A.
- 申请号:
- CA2962922
- 公开号:
- CA2962922A1
- 申请日:
- 2015.09.28
- 申请国别(地区):
- CA
- 年份:
- 2016
- 代理人:
- 摘要:
- The invention provides compounds effective as sphingosine-1 -phosphate receptor modulators for treatment of cardiopulmonary diseases, such as hypertension (including malignant hypertension), angina, myocardial infarction, cardiac arrhythmias, congestive heart failure, coronary heart disease, atherosclerosis, angina pectoris, dysrhythmias, cardiomyothopy (including hypertropic cardiomyothopy), heart failure, cardiac arrest, bronchitis, asthma, chronic obstructive pulmonary disease, cystic fibrosis, croup, emphysema, pleurisy, pulmonary fibrosis, pneumonia, pulmonary embolus, pulmonary hypertension, mesothelioma, ventricular conduction abnormalities, complete heart block, adult respiratory distress syndrome, sepsis syndrome, idiopathic pulmonary fibrosis, scleroderma, systemic sclerosis, retroperitoneal fibrosis, prevention of keloid formation, or cirrhosis.
- 来源网站:
- 中国工程科技知识中心
- 来源网址:
- http://www.ckcest.cn/home/
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