A multi-chamber syringe with a syringe body having a wall which encloses a hollow space. The syringe body has a syringe outlet and an opening for receiving a piston displaceable in the hollow space, where at least one displaceable stopper is arranged in the hollow space and divides the hollow space into a first chamber, for receiving a first substance, and a second chamber, for receiving a second substance. The syringe body also has a channel through which the first substance can flow from the first chamber into the second chamber when the stopper is positioned in such a way that the channel connects the first chamber to the second chamber, where the channel is formed by a material cutout in the wall on a side of the wall facing toward the hollow space.