A medical mask system is provided that detects aspiration and/or vomit or misdirected oropharyngeal secretions, alerts medical staff, and removes any effluent to prevent pulmonary aspiration. The mask system includes a mask body for covering the wearers mouth that is integrated with at least one aspiration-detecting sensor. The aspiration-detecting sensor is configured for detecting aspiration or effluent and is configured to provide an aspiration-detected signal. The signal is received by both an alerting device and a suction assembly that is actuated to provide suction to tubing attached to the mask body to remove any effluent from the mask body. The aspiration-detecting sensor may include, for example, one or more of a pH sensor, a pressure sensor, an oxygen flow sensor, an acoustic sensor, or an object recognition sensor. The alert, for example, may be provided to a nurses station, at a patients room, or to a mobile application.
